Not known Factual Statements About pkrrating
3B). R526 with the loop among αJ and αI anchors the C-terminal portion of the activation loop by forming a salt bridge with E458 at the base of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the most crucial chain carbonyl of R413. The tip of your activation segment is stabilized by a hydrogen bond amongst Y454 and E480 from αF. In th